Conformation of permethylated cyclodextrins and the host-guest geometry of their inclusion complexes
✍ Scribed by Kazuaki Harata; Kaneto Uekama; Masaki Otagiri; Fumitoshi Hirayama
- Publisher
- Springer Netherlands
- Year
- 1984
- Tongue
- English
- Weight
- 806 KB
- Volume
- 1
- Category
- Article
- ISSN
- 0923-0750
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## Abstract The interaction between doxepin, a member of the tricyclic antidepressant (TCA) class of drugs, with β‐cyclodextrin (β‐CD) was investigated using NMR. Several TCAs have been reported to form a complex with β‐CD having 1:1 stoichiometry. Previous results from UV‐visible spectroscopy, flu
## Abstract [CpM(CO)__~n~__Cl] complexes with M = Fe (__n__ = 2) and Mo (__n__ = 3) have been immobilised in plain β‐cyclodextrin (β‐CD) and permethylated β‐CD (TRIMEB) by methods tailored according to the stabilities and solubilities of the individual components. Four adducts were obtained with a