✦ LIBER ✦

Conformation of nefopam hydrochloride, a novel analgesic

✍ Scribed by Robert Glaser; Shmuel Cohen; David Donnell; Israel Agranat

Publisher: John Wiley and Sons
Year: 1986
Tongue: English
Weight: 379 KB
Volume: 75
Category: Article
ISSN: 0022-3549
DOI: 10.1002/jps.2600750810

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Solid-state structure of orphenadrine hy

Solid-state structure of orphenadrine hydrochloride and conformational comparisons with diphenhydramine hydrochloride and nefopam hydrochloride

✍ Robert Glaser; David Donnell; Knut Maartmann-Moe 📂 Article 📅 1992 🏛 John Wiley and Sons 🌐 English ⚖ 525 KB

Stereoisomer differentiation for the ana

Stereoisomer differentiation for the analgesic drug nefopam hydrochloride using modeling studies of serotonin uptake area

✍ Robert Glaser; David Donnell 📂 Article 📅 1989 🏛 John Wiley and Sons 🌐 English ⚖ 461 KB

Assessment of the analgesic efficacy of

Assessment of the analgesic efficacy of nefopam hydrochloride after upper abdominal surgery: A study using patient controlled analgesia

✍ T. T. C. McLintock; Dr. G. N. C. Kenny; J. C. Howie; C. S. McArdle; S. Lawrie; H 📂 Article 📅 1988 🏛 John Wiley and Sons 🌐 English ⚖ 333 KB

1H and 13C NMR conformational studies on

1H and 13C NMR conformational studies on quaternary nitrogen derivatives of the analgesic drug nefopam

✍ Robert Glaser; Ariel Peleg; Shimona Geresh 📂 Article 📅 1990 🏛 John Wiley and Sons 🌐 English ⚖ 756 KB

## Abstract Nitrogen quaternization in the analgesic nefopam [(±)‐3,4,5,6‐tetrahydro‐5‐methyl‐1‐phenyl‐1__H__‐2,5,‐ benzoxazocine hydrochloride] by either __N__‐trideuteriomethylation or __N__‐oxidation affords reaction product diastereomeric mixtures differing in __N__‐configuration. The axial to

GLC determination of nanogram quantities

GLC determination of nanogram quantities of a new analgesic, nefopam, in human plasma

✍ D. Schuppan; C. S. Hansen; R. E. Ober 📂 Article 📅 1978 🏛 John Wiley and Sons 🌐 English ⚖ 414 KB 👁 1 views

NMR studies on conformational and N-conf

NMR studies on conformational and N-configurational interconversion in 3-methyl derivatives of the non-narcotic analgesic drug nefopam

✍ Robert Glaser; Jeanine Blumenfeld; Shimona Geresh 📂 Article 📅 1993 🏛 John Wiley and Sons 🌐 English ⚖ 887 KB

## Abstract Two different __N__‐configurations and two different eight‐membered ring conformations were found in the diastereomeric crystalline (1__R__,3__S__)/(1__S__,3__R__)‐ and (1__S__,3__R__)/(1__S__,3__S__)‐3‐methylnefopam hydrochloride salts. ^1^H and ^13^C NMR spectroscopy showed that both