Conformation of cyclosporin A in polar solvents
β Scribed by KO, SOO YOUNG ;DALVIT, CLAUDIO
- Book ID
- 115099331
- Publisher
- Wiley (Blackwell Publishing)
- Year
- 2009
- Tongue
- English
- Weight
- 236 KB
- Volume
- 40
- Category
- Article
- ISSN
- 0367-8377
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## Abstract New investigations of cyclosporin A in CDCl~3~ have been performed to obtain additional and more accurate distance restraints than utilized in our previous studies of cyclosporin A. Buildβup rates at 600 MHz using 6 different mixing times at low temperatures (252.5 K) were determined an
Fast radiationless deactivation Se -+ S,-, of a photoexcited state through a "funnel" is discussed. Thz experimental rates of such transitions cannot be ehplained in general by a one-dimensional model considem only the an&e of isomerizatIon. Inclusion of the full number of degrees of freedom Ia& \*-