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Conformation-independent QSAR on c-Src tyrosine kinase inhibitors

โœ Scribed by Comelli, Nieves C.; Ortiz, Erlinda V.; Kolacz, Magdalena; Toropova, Alla P.; Toropov, Andrey A.; Duchowicz, Pablo R.; Castro, Eduardo A.

Book ID
121831186
Publisher
Elsevier Science
Year
2014
Tongue
English
Weight
472 KB
Volume
134
Category
Article
ISSN
0169-7439

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โœ Ninad V. Prabhu; Subeeh A. Siddiqui; John S. McMurray; B. Montgomery Pettitt ๐Ÿ“‚ Article ๐Ÿ“… 2001 ๐Ÿ› Wiley (John Wiley & Sons) ๐ŸŒ English โš– 444 KB ๐Ÿ‘ 2 views

Conformational searches on three closely related pp60 c-src protein tyrosine kinase inhibitors of varying potencies were performed to determine a structural basis for their activity. The first was a linear peptide (PDNEYAFFQf), the second its 10-membered cyclic analogue, and the third a cyclic analo