Conformation and structure of 2-amino-8-(β-d-ribofuranosyl)imidazo [1,2-a]-s-triazin-4-one (5-aza-7-deaza guanosine), a potent antiviral nucleoside

2-Amino-8-(2-deoxy-2-fluoro-β-D-arabinof

2-Amino-8-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)imidazo[1,2-a]-1,3,5-triazin-4(8H)-one: Synthesis and Conformation of a 5-Aza-7-deazaguanine Fluoronucleoside

✍ Virginie Glaçon; Frank Seela 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 German ⚖ 112 KB

## Abstract Nucleobase‐anion glycosylation of 2‐[(2‐methyl‐1‐oxopropyl)amino]imidazo[1,2‐__a__]‐1,3,5‐triazin‐4(8__H__)‐one (**6**) with 3,5‐di‐__O__‐benzoyl‐2‐deoxy‐2‐fluoro‐__α__‐D‐arabinofuranosyl bromide (**8**) furnishes a mixture of the benzoyl‐protected anomeric 2‐amino‐8‐(2‐deoxy‐2‐fluoro‐D