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Conformation and dynamics associated with the site of attachment of a carcinogen to a nucleotide

โœ Scribed by Frederick E. Evans; Dwight W. Miller


Book ID
115756307
Publisher
Elsevier Science
Year
1982
Tongue
English
Weight
415 KB
Volume
108
Category
Article
ISSN
0006-291X

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A novel adenosine triphosphate analog wi
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We have synthesized 2'-deoxy-2'-iodoadenosine-5'-triphosphate (2'-IATP), a heavy-atom analog of adenosine-5'-triphosphate. This compound was made for X-ray structural studies to target the nucleotide site of ATP binding proteins. It was diffused successfully into crystals of the microtubule-based mo