Confocal imaging of sebaceous gland hyperplasia in vivo to assess efficacy and mechanism of pulsed dye laser treatment

✍ Scribed by Gonz�lez, Salvador; White, W. Matthew; Rajadhyaksha, Milind; Anderson, R. Rox; Gonz�lez, Ernesto

• Publisher: John Wiley and Sons
• Year: 1999
• Tongue: English
• Weight: 391 KB
• Volume: 25
• Category: Article
• ISSN: 0196-8092
• DOI: 10.1002/(sici)1096-9101(1999)25:1<8::aid-lsm2>3.0.co;2-8

✦ Synopsis

Background and Objective

: This case demonstrates, for the first time, the use of in vivo confocal imaging to assess the efficacy of laser treatment of a skin lesion with a vascular component. Study Design/Patient and Method: A patient with lesions of sebaceous gland hyperplasia was histologically imaged in vivo before and after treatment with a 585 nm pulse dye laser (PDL) by using a near-infrared, confocal reflectance microscope. Hyperplastic sebaceous ducts and sebaceous glands were seen with high resolution in vivo. Prominent dermal vasculature was viewed as well as its selective targeting by PDL. Conclusion: Our results confirm the previously reported successful treatment of sebaceous gland hyperplasia with the 585 nm PDL. Lasers Surg. Med. 25:8-12, 1999.