Confirmation of linkage between the loci for HL-A and glyoxalase I
✍ Scribed by J. Kömpf; S. Bissbort; F. Schunter
- Publisher
- Springer
- Year
- 1976
- Tongue
- English
- Weight
- 104 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0340-6717
No coin nor oath required. For personal study only.
✦ Synopsis
Linkage analysis of 7 families with 30 children confirmed previous findings of the linkage between HL-A and GLO. Out of 28 families with 90 children the highest lod score value obtained was + 8.887 (recombination fraction = 0.1).
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The cost of experiments aimed at determining linkage between marker loci and quantitative trait loci (QTL) was investigated as a function of marker spacing and number of individuals scored. It was found that for a variety of experimental designs, fairly wide marker spacings (ca. 50 cM) are optimum o
The power of experiments aimed at detecting linkage between a quantitative locus and a marker locus, both segregating in the backross or F2 generation of a cross between two inbred lines, is examined. Given that the two lines are close to fixation for alternative alleles of both marker locus and qua