✦ LIBER ✦

Confirmation of early menopause in fragile X carriers

✍ Scribed by Partington, M. W.; Moore, D. York; Turner, G. M.

Publisher: John Wiley and Sons
Year: 1996
Tongue: English
Weight: 226 KB
Volume: 64
Category: Article
ISSN: 0148-7299
DOI: 10.1002/(sici)1096-8628(19960809)64:2<370::aid-ajmg27>3.0.co;2-b

No coin nor oath required. For personal study only.

✦ Synopsis

Fragile X carriers have a median age of menopause 6 to 8 years earlier than women in the general population, with 28% experiencing premature ovarian failure defined as menopause before the age of 40 years. This information was obtained from 203 returned questionnaires from women in the UK Fragile X Society.

📜 SIMILAR VOLUMES

Fragile X: Carrier detection in pregnanc

Fragile X: Carrier detection in pregnancy

✍ Tommerup, Niels ;Holmgren, Gösta ;Steinbach, Peter ;Opitz, John M. ;Reynolds, Ja 📂 Article 📅 1986 🏛 John Wiley and Sons 🌐 English ⚖ 175 KB 👁 1 views

Sex chromosome aneuploidy in fragile X c

Sex chromosome aneuploidy in fragile X carriers

✍ Nielsen, Karen Brøndum ;Opitz, John M. ;Reynolds, James F. 📂 Article 📅 1986 🏛 John Wiley and Sons 🌐 English ⚖ 334 KB 👁 2 views

Neuropathic features in fragile X premut

Neuropathic features in fragile X premutation carriers

✍ Elizabeth Berry-Kravis; Christopher G. Goetz; Maureen A. Leehey; Randi J. Hagerm 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 125 KB 👁 2 views

Inactivation pattern of the fragile X in

Inactivation pattern of the fragile X in heterozygous carriers

✍ Fryns, Jean-Pierre ;Berghe, Herman Van Den 📂 Article 📅 1988 🏛 John Wiley and Sons 🌐 English ⚖ 257 KB 👁 1 views

Neurobehavioral phenotype in carriers of

Neurobehavioral phenotype in carriers of the fragile X premutation

✍ Johnston, Cindy ;Eliez, Stephan ;Dyer-Friedman, Jennifer ;Hessl, David ;Glaser, 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 91 KB 👁 1 views

There have been contradictory ®ndings in the fragile X (fraX) literature about possible neurocognitive and psychological symptoms due to the fraX premutation (pM). The purpose of the present study was to investigate the relationship between CGG repeat length and neurobehavioral functioning in carrie

Prenatal diagnosis and carrier detection

Prenatal diagnosis and carrier detection in fragile X

✍ Von Koskull, Harriet ;Nordström, Ann-Marie ;Salonen, Riitta ;Peltonen, Leena 📂 Article 📅 1992 🏛 John Wiley and Sons 🌐 English ⚖ 498 KB 👁 1 views

## Abstract Prenatal diagnosis was performed in 81 cases at risk for the fragile X syndrome. There were 12 fra (X)‐positive cases, two of which showed low expression in cultured amniotic fluid cells. FUdR and high thymidine were used for induction of fra(X) (q27.3) expression in all cases. In 21 ca