Confirmation of down syndrome critical region by FISH analysis in a patient with add(21)(p11)

Down syndrome with biparental inheritanc

Down syndrome with biparental inheritance of der(14q21q) and maternally derived trisomy 21: Confirmation by fluorescent in situ hybridization and microsatellite polymorphism analysis

✍ Rajangam, Sayee; Michaelis, Ron C.; Velagaleti, GopalRao V. N.; Lincoln, Shavant 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 306 KB 👁 2 views

## Individuals with translocation Down syndrome (DS) often inherit the rearranged chromosome from a carrier parent. DS due to inheritance of one Robertsonian or derivative (14q21q) from one parent and a second der(14q21q) in addition to a free chromosome 21 from the other parent are rarely documen