Confirmation of a particular but nonspecific metacarpophalangeal pattern profile in patients with the Smith-Magenis syndrome due to interstitial deletion of 17p

Review of disrupted sleep patterns in Sm

Review of disrupted sleep patterns in Smith–Magenis syndrome and normal melatonin secretion in a patient with an atypical interstitial 17p11.2 deletion

✍ Eilis A. Boudreau; Kyle P. Johnson; Angela R. Jackman; Jan Blancato; Marjan Huiz 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 346 KB 👁 2 views

## Abstract Smith–Magenis syndrome (SMS) is a disorder characterized by multiple congenital anomalies and behavior problems, including abnormal sleep patterns. It is most commonly due to a 3.5 Mb interstitial deletion of chromosome 17 band p11.2. Secretion of melatonin, a hormone produced by the pi