The structural assignment of 2-and 4-endo-iodobicydo[3.3.l]non-6-ene-3-endo-~bonitriles was accomplished by evaluation of their COSY spectra. All 'H and =C signals were identified unequivocally. Vicioal 'H-lH coupling constants, NOESY experiments and iodine substitnent effects on the -C chemical shi
Configurational assignment by NMR spectroscopy of stereoisomeric 2,6-dimethyl-tricyclo[5.2.1.02,6]dec-3-enes and decanes: Albene and isoalbene
✍ Scribed by Wolfgang Kreiser; Lother Janitschke; Ludger Ernst
- Publisher
- Elsevier Science
- Year
- 1978
- Tongue
- French
- Weight
- 165 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0040-4020
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## Abstract 4‐[3‐[4‐(2‐Methoxyphenyl)piperazin‐1‐yl]propoxy]‐4‐aza‐tricyclo[5.2.1.02,6]dec‐8‐ene‐3,5‐dione (4), a potent and selective 5‐HT~1A~ agonist, was labeled by ^11^C‐methylation of the corresponding desmethyl analogue 3 with ^11^C‐methyl triflate. The precursor molecule 3 was synthesized fr