## Abstract When as many as four vicinal couplings occur between four protons situated on three carbon atoms of a cyclobutane ring, one can employ the Karplus relation to assign the configuration of substituents at the remaining positions and make some inferences about the stereochemistry. Four exa
Configuration and conformation of all four cocaines from nmr spectra
โ Scribed by A. Sinnema; L. Maat; Miss A. J. van der Gugten; H. C. Beyerman
- Publisher
- Elsevier Science
- Year
- 2010
- Tongue
- English
- Weight
- 623 KB
- Volume
- 87
- Category
- Article
- ISSN
- 0165-0513
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As shown in the preceding note 2) , a 75% pure [ lZ]annulene can be synthesized by UV irradiation of syn-tricyclo[ 8.2.0.0 2'9]d d o eta-3.5.7.1i-tetraene at -ilO"C. We have investigated the temperature dependent NMR spectrum of this compound in order i) to establish its configuration in terms of th