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Confidence intervals for relative risk estimates from affected-sib-pair data

✍ Scribed by Heather J. Cordell; Jane M. Olson

Publisher: John Wiley and Sons
Year: 1997
Tongue: English
Weight: 43 KB
Volume: 14
Category: Article
ISSN: 0741-0395
DOI: 10.1002/(sici)1098-2272(1997)14:6<593::aid-gepi7>3.0.co;2-0

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✦ Synopsis

Confidence intervals for relative risk parameters estimated using affected-sib-pair data are derived and evaluated for two markers showing previous evidence of linkage to bipolar illness. For D18S41 we found some evidence, and for D18S37 stronger evidence, of relative risks greater than 1, although in both cases the estimated confidence intervals for the parameters are wide.

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