Conessine isolated from Holarrhena floribunda

✍ Scribed by Lannang, Alain Meli ;Anjum, Shazia ;Tangmouo, Jean Gustave ;Krohn, Karsten ;Choudhary, M. Iqbal

• Book ID: 104492047
• Publisher: International Union of Crystallography
• Year: 2007
• Tongue: English
• Weight: 340 KB
• Volume: 63
• Category: Article
• ISSN: 1600-5368
• DOI: 10.1107/s1600536807051215

✦ Synopsis

The title compound, C~24~H~40~N~2~, has been isolated from Holarrhena floribunda G. Don. (Apocynaceae). The compound has a pentacyclic steroidal nucleus; the ring junctions share the same stereochemistry reported for this class of compounds. Of the three six-membered rings, rings A and C adopt a chair-like and ring B forms a half-chair-like conformation. The cyclopentane ring D shows a half-chair conformation and the methylpyrrolidine ring E adopts an envelope conformation. The dimethylamino substituent in ring A is equatorially oriented.