Conduction velocity versus amplitude analysis: Evidence for demyelination in diabetic neuropathy
✍ Scribed by John R. Wilson; James D. Stittsworth Jr; Abdul Kadir; Morris A. Fisher
- Publisher
- John Wiley and Sons
- Year
- 1998
- Tongue
- English
- Weight
- 93 KB
- Volume
- 21
- Category
- Article
- ISSN
- 0148-639X
No coin nor oath required. For personal study only.
✦ Synopsis
Motor conduction velocities (CVs) were correlated with distal compound muscle action potential (CMAP) amplitudes for tibial, peroneal, and median nerves in patients with biopsy-proven chronic inflammatory demyelinating polyneuropathy (CIDP), diabetic neuropathy, and amyotrophic lateral sclerosis. Only in the diabetic patients did CV significantly correlate with CMAP amplitude. The data show that diabetic neuropathy produces conduction velocity slowing that cannot be explained by axon loss alone, and that differentiation between diabetic neuropathy and CIDP in an individual nerve is difficult.