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Conditions influencing yield and analysis of 8-hydroxy-2′-deoxyguanosine in oxidatively damaged DNA

✍ Scribed by R.A. Floyd; M.S. West; K.L. Eneff; J.E. Schneider; P.K. Wong; D.T. Tingey; W.E. Hogsett

Book ID
107714902
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
453 KB
Volume
188
Category
Article
ISSN
0003-2697

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Oxidative DNA damage and 8-hydroxy-2-deo
Oxidative DNA damage and 8-hydroxy-2-deoxyguanosine DNA glycosylase/apurinic lyase in human breast cancer
✍ Donghui Li; Weiqing Zhang; Jijiang Zhu; Ping Chang; Aysegul Sahin; Eva Singletar 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 485 KB 👁 1 views

To test the hypothesis that oxidative stress is involved in breast cancer, we compared the levels of 8-hydroxy-2-deoxyguanosine (8-oxo-dG), an oxidized DNA base common in cells undergoing oxidative stress, in normal breast tissues from women with or without breast cancer. We found that breast cancer