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Conditioning of the early behavioral response to apomorphine in the rotational model of Parkinson's disease

✍ Scribed by E. Burunat; R. Castro; M.D. Díaz-Palarea; M. Rodríguez

Book ID
115881644
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
385 KB
Volume
145
Category
Article
ISSN
0014-2999

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The duration of the motor response to ap
The duration of the motor response to apomorphine boluses is conditioned by the length of a prior infusion in Parkinson's disease
✍ Julia Vaamonde; José M. Flores; Roberto Weisser; Ramón Ibañez; José A. Obeso 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 457 KB

## Abstract “Pulsatile” administration of levodopa has been invocated a relevant factor for motor fluctuations in Parkinson's disease (PD). We studied dopaminergic sensitivity to apomorphine in 10 parkinsonian patients with motor fluctuations. Patients were tested as follows: the minimal effective