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Conditional knockout of heparin-binding epidermal growth factor-like growth factor in the liver accelerates carbon tetrachloride-induced liver injury in mice

✍ Scribed by Takayo Takemura; Yuichi Yoshida; Shinichi Kiso; Yukiko Saji; Hisao Ezaki; Mina Hamano; Takashi Kizu; Mayumi Egawa; Norihiro Chatani; Kunimaro Furuta; Yoshihiro Kamada; Ryo Iwamoto; Eisuke Mekada; Shigeki Higashiyama; Norio Hayashi; Tetsuo Takehara


Book ID
117966640
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
764 KB
Volume
43
Category
Article
ISSN
1386-6346

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Role of heparin-binding epidermal growth
✍ Shinichi Kiso; Sumio Kawata; Shinji Tamura; Shigeki Higashiyama; Nobuyuki Ito; H πŸ“‚ Article πŸ“… 1995 πŸ› John Wiley and Sons 🌐 English βš– 887 KB

Several growth factors including hepatocyte growth factor (HGF) have been implicated in the regulation of liver regeneration. Recently, we reported that heparin-binding epidermal growth factor (EGF)-like growth factor (HB-EGF) has hepatotrophic effects in vitro. We investigated the role of HB-EGF as