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Conditional inactivation of Sox9: A mouse model for campomelic dysplasia

✍ Scribed by Ralf Kist; Heinrich Schrewe; Rudi Balling; Gerd Scherer


Publisher
John Wiley and Sons
Year
2002
Tongue
English
Weight
360 KB
Volume
32
Category
Article
ISSN
1526-954X

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Campomelic dysplasia is a malformation syndrome with multiple symptoms including characteristic shortness and bowing of the long bones (campomelia). CD, often lethal due to airway malformations, is caused by heterozygous mutations in SOX9, an SRY-related gene regulating testis and chondrocyte develo