𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Conditional ablation of neurones in transgenic mice

✍ Scribed by Isles, Anthony R. ;Ma, Dan ;Milsom, Chloe ;Skynner, Michael J. ;Cui, Wei ;Clark, John ;Keverne, Eric B. ;Allen, Nicholas D.

Publisher
John Wiley and Sons
Year
2001
Tongue
English
Weight
341 KB
Volume
47
Category
Article
ISSN
0022-3034

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Conditional inactivation of the Cacna1a
Conditional inactivation of the Cacna1a gene in transgenic mice
✍ Boyan Todorov; Rob C.G. van de Ven; Simon Kaja; Ludo A.M. Broos; Sjef J. Verbeek πŸ“‚ Article πŸ“… 2006 πŸ› John Wiley and Sons 🌐 English βš– 398 KB

Ca(v)2.1 (P/Q-type) voltage-gated calcium channels play an important role in neurotransmitter release at many brain synapses and at the neuromuscular junction. Mutations in the CACNA1A gene, encoding the pore forming alpha(1) subunit of Ca(v)2.1 channels, are associated with a wide spectrum of neuro

Transgenic mice for conditional gene man
Transgenic mice for conditional gene manipulation in astroglial cells
✍ Michal Slezak; Christian GΓΆritz; Aurore Niemiec; Jonas FrisΓ©n; Pierre Chambon; D πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 English βš– 763 KB

## Abstract Astrocytes are thought to exert diverse functions in the brain, but it has been difficult to prove this __in vivo__ because of a scarcity of tools to manipulate these cells. Here, we report the generation of new transgenic mouse lines that allow for conditional gene ablation in astrocyt

Expression of conditional cre recombinas
Expression of conditional cre recombinase in epithelial tissues of transgenic mice
✍ Fang Wen; Grace Cecena; Varinia Munoz-Ritchie; Elaine Fuchs; Pierre Chambon; Rob πŸ“‚ Article πŸ“… 2003 πŸ› John Wiley and Sons 🌐 English βš– 451 KB

## Abstract Summary: Keratin 18 (K18) expression is a defining characteristic of internal epithelial cells of mammals. Here, we used the K18 gene and an internal ribosome entry site (IRES) to express green fluorescent protein, human placental alkaline phosphatase, and a modified Cre recombinase in

Bax ablation protects against hepatic is
Bax ablation protects against hepatic ischemia/reperfusion injury in transgenic mice
✍ Ziv Ben-Ari; Orit Pappo; Yelena Cheporko; Natali Yasovich; Daniel Offen; Asher S πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 English βš– 506 KB

Apoptosis appears to be a central mechanism of cell death following reperfusion of the ischemic liver. The aim of this study was to determine the effect of decreased expression of the proapoptotic Bax gene on hepatic apoptotic warm ischemia/reperfusion (I/R) injury. Three groups of mice were studied

hGFAP-cre transgenic mice for manipulati
hGFAP-cre transgenic mice for manipulation of glial and neuronal function in vivo
✍ Lang Zhuo; Martin Theis; Ikuri Alvarez-Maya; Michael Brenner; Klaus Willecke; Al πŸ“‚ Article πŸ“… 2001 πŸ› John Wiley and Sons 🌐 English βš– 921 KB

## Abstract With the goal of performing astrocyte‐specific modification of genes in the mouse, we have generated a transgenic line expressing Cre recombinase under the control of the human glial fibrillary acidic protein (hGFAP) promoter. Activity was monitored by crossing the hGFAP‐cre transgenics