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Condensin I Interacts with the PARP-1-XRCC1 Complex and Functions in DNA Single-Strand Break Repair

✍ Scribed by Jason T. Heale; Alexander R. Ball Jr.; John A. Schmiesing; Jong-Soo Kim; Xiangduo Kong; Sharleen Zhou; Damien F. Hudson; William C. Earnshaw; Kyoko Yokomori


Book ID
116754129
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
932 KB
Volume
21
Category
Article
ISSN
1097-2765

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## Abstract X‐ray cross complementing 1 (XRCC1) protein has been suggested to bind to DNA single‐strand breaks (SSBs) and organize protein interactions that facilitate efficient DNA repair. Using four site‐specifically modified human XRCC1 mutant expression systems and functional complementation as