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Condensed pyridine bases. Reactions of 1-oxo-3,3,6-trimethyl-1,2,3,4-tetrahydrobenzo[b]furo-, benzo[b]thieno-, and indolo[2,3-c]quinolines with electrophilic reagents

โœ Scribed by S. V. Tolkunov; M. N. Kal'nitskii; A. I. Khizhan; S. Yu. Suikov; M. Yu. Zubritskii; V. I. Dulenko


Publisher
Springer US
Year
1995
Tongue
English
Weight
531 KB
Volume
31
Category
Article
ISSN
0009-3122

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Alkylation of 1,2,4-triazine-6-thiones with 4-iodobutyne, followed by oxidation to the sulfoxide and intramolecular cycloaddition (at room temperature), gives 2,3-dihydrothieno[2,3-c]pyridines, which are readily dehydrated with acetic anhydride to thieno[2,3\_c]pyridines. The same series of reactio