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Condensed imidazo-1,2,4-azines 22. Alkylation of 5H-imidazo[1,2-b]-1,2,4-triazepin-4-ones

✍ Scribed by V. P. Kruglenko; V. A. Idzikovskii; N. N. Kobets; M. V. Povstyanoi

Publisher: Springer US
Year: 1990
Tongue: English
Weight: 239 KB
Volume: 26
Category: Article
ISSN: 0009-3122
DOI: 10.1007/bf00499416

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✦ Synopsis

Substituted 5H-imidazo[l,2-b]-l,2,4-triazepin-4-ones react with alkyl (alkenyl) halides, 2-chloroethanol, glycerin dichlorohydrin, haloacetic acids, the methyl ester and amide of menochloroacetic acid in a methanol-sodium methylate system to form N(s)-alkylation products, and with hydroxylamino-O-sulfonic acid to form 5-aminoimidazo[l,2-b]-l,2,4-triazepin-4-one.

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