✦ LIBER ✦
Condensed 1,2,4-Triazines I: Behaviour of Phenanthro[9,10-e]-1,2,4-triazine Derivatives Towards Alkylating and Reducing Agends, Grignard Reagents, and Amines
✍ Scribed by Mohamed Mohamed Mohamed Sallam; Yehia Abdu Ibrahim; Sayed Abdel-Latif Abdel-Hady
- Publisher
- John Wiley and Sons
- Year
- 1976
- Tongue
- German
- Weight
- 372 KB
- Volume
- 59
- Category
- Article
- ISSN
- 0018-019X
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
Alkylation of 3‐hydroxy‐phenanthro[9,10‐e]1,2,4‐triazine (1a) yielded the N(2)‐alkyl derivatives 2a–2b; alkylation of the 3‐mercapto analogue 1b yielded the S‐alkyl derivatives 1f–1i.
1a–1b reacted with alkyl and aralkylmagnesium halides to yield the corresponding 3‐hydroxy‐, and 3‐mercapto‐5‐alkyl‐(aralkyl)‐phenanthro[9,10‐e]2,3,4,5‐tetrahydro‐1,2,4‐triazines 5a–5f.
Reduction of 1a yielded the hexahydrotriazine derivative 7. Amination of 1c yielded the 3‐amino derivatives 1j–1o after prolonged heating.