## Abstract The reaction of enolates of α‐unsubstituted carboxamides 3 with diphenyl phosphorazidate (DPPA) and di(__tert__‐butyl) dicarbonate (‘Boc anhydride’) in THF at −78° yielded 2‐{[(__tert__‐butoxy)carbonyl]amino}carboxamides 5 (__Scheme 2__) which are derivatives of α‐amino acids. In this r
Condensation of α-Amino Acid with Amine in the Absence of a Coupling Agent.
✍ Scribed by Jun-ichi Yamaguchi; Shinya Nagai; Emi Fukuoka; Takayuki Suyama
- Publisher
- John Wiley and Sons
- Year
- 2004
- Weight
- 96 KB
- Volume
- 35
- Category
- Article
- ISSN
- 0931-7597
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Abstract
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The inversion of configuration of L-alanine can be carried out by combining its selective oxidation in the presence of NAD + and L-alanine dehydrogenase, electrochemical regeneration of the NAD + at a carbon felt anode, and reductive amination of pyruvate, i.e., reduction of its imino derivative at
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