Concurrent thrombotic thrombocytopenic purpura and immune thrombocytopenic purpura in an HIV-positive patient: Case report and review of the literature

✍ Scribed by Yospur, Lisa S.; Sun, Nora C.J.; Figueroa, Priscilla; Niihara, Yutaka

• Publisher: John Wiley and Sons
• Year: 1996
• Tongue: English
• Weight: 495 KB
• Volume: 51
• Category: Article
• ISSN: 0361-8609
• DOI: 10.1002/(sici)1096-8652(199601)51:1<73::aid-ajh12>3.0.co;2-c

✦ Synopsis

Immune thrombocytopenlc purpura (ITP) and thrombotic thrombocytopenlc purpura (lTP) have each been associated with HIV Infection. Sequential occurrence of these two dlseases with a disease-free interval has been occasionally reported In the literature, whereas simultaneous manifestations of these two diseases have not been described. Here, we report an AIDS patient who was lnltlally diagnosed as having l T P and showed an apparent partial response to plasmapheresls but was found to have a clinical course slmllar to ITP. Although precise mechanisms for the development of TTP and ITP In these patients are unclear, we offer several hypotheses. It is important to recognize that these two processes may be seen concurrently.