Concurrent radiation, mitomycin C and 5-fluorouracil in poor prognosis carcinoma of cervix: Preliminary results of a phase I-II study
β Scribed by Gillian Thomas; Alon Dembo; Francis Beale; Helen Bean; Raymond Bush; James Herman; John Pringle; Gayle Rawlings; Jeremy Sturgeon; Sheldon Fine; Barbara Black
- Publisher
- Elsevier Science
- Year
- 1984
- Tongue
- English
- Weight
- 701 KB
- Volume
- 10
- Category
- Article
- ISSN
- 0360-3016
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π SIMILAR VOLUMES
To determine the feasibility and toxicity of combining leucovorin (CF) with a 5fluorouracil(5-FU) combination chemotherapy regimen currently accepted by many as standard treatment for gastric cancer, CF (500 mg/m') was administered in combination with the Georgetown S-FU, doxorubicin, and mitomycin
In a Phase I1 study, 50 patients with advanced breast cancer were treated with a combination of 5fluorouracil(lOO0 mg/m2 on days 1 and 2) and mitomycin C (6 mg/m2 on day 2) (FuMi regimen). The courses were repeated every third to sixth week. Although 35 patients had previously received combination c
## Abstract ## BACKGROUND The authors conducted a Phase I/II study in patients with a poor prognosis who had locally advanced squamous cell carcinoma of the head and neck (SCCHN) and who were treated initially with induction chemotherapy. Patients were treated with weekly docetaxel and concurrent