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Concurrent loss of heterozygosity and copy number analysis in adenoid cystic carcinoma by SNP genotyping arrays

✍ Scribed by Yu, Yongtao; Baras, Alexander S; Shirasuna, Kanemitsu; Frierson, Henry F; Moskaluk, Christopher A


Book ID
109886140
Publisher
Nature Publishing Group
Year
2007
Tongue
English
Weight
358 KB
Volume
87
Category
Article
ISSN
0023-6837

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## Abstract We have undertaken an extensive high‐resolution analysis of loss of heterozygosity (LOH) in 30 high grade gliomas using the Affymetrix 100K SNP mapping array. Only 70% of LOH events were accompanied by a copy number loss (CNA~loss~), and of the other 30%, the distal region of 17p prefer