Concurrent electroconvulsive therapy in patients receiving reboxetine

✍ Scribed by Ashok N. Singh

• Book ID: 101281981
• Publisher: John Wiley and Sons
• Year: 1999
• Tongue: English
• Weight: 53 KB
• Volume: 14
• Category: Article
• ISSN: 0885-6222
• DOI: 10.1002/(sici)1099-1077(199910)14:7<509::aid-hup130>3.0.co;2-p

✦ Synopsis

There are few studies of the potential interaction between antidepressants and electroconvulsive therapy (ECT), although there is a theoretical risk of serotonin syndrome when ECT is used in patients receiving selective serotonin reuptake inhibitors. There may also be an increased cardiovascular risk during ECT therapy in patients receiving tricyclic antidepressants. Reboxetine is a novel selective noradrenaline reuptake inhibitor, with actions speci®c to the noradrenergic system and negligible anity for other neurotransmitter receptors. Here we report two cases in which ECT was used in patients receiving reboxetine. In both cases the episodes of ECT appeared uncomplicated by the concomitant administration of reboxetine. We suggest that the combined use of ECT with reboxetine is well tolerated.