## Abstract ## BACKGROUND: A randomized phase 2 study was performed to investigate the efficacy/toxicity of combining concomitant boost radiation and weekly carboplatin/paclitaxel with or without amifostine in patients with locally advanced squamous cell carcinoma of the head and neck (SCCHN). ##
Concurrent Chemoradiation with Carboplatin and Paclitaxel with or without Concomitant Boost in Advanced Inoperable Head and Neck Cancers - Efficacy and Toxicity
✍ Scribed by S.I. Temming; M. Kocher; J. Klussmann; S. Preuss; O. Guntinas-Lichius; R. Semrau; R.P. Müller
- Book ID
- 108150322
- Publisher
- Elsevier Science
- Year
- 2009
- Tongue
- English
- Weight
- 40 KB
- Volume
- 75
- Category
- Article
- ISSN
- 0360-3016
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract ## Background. The purpose of this study was to evaluate the efficacy and toxicity of radiotherapy and concomitant 5‐fluorouracil (5‐FU) and mitomycin‐C infusion in inoperable head and neck cancer. ## Methods. Seventy‐six patients (86% men, 14% women), mean age 57 years, with primary
To evaluate the toxicity of intensity-modulated radiotherapy with simultaneous integrated boost (SIB-IMRT) in head and neck cancer patients treated using a protocol comprising 66 Gy to the PTV1 (planning target volume; region of macroscopic tumour) and 60 Gy and 54 Gy to the regions with high risk (
## Abstract ## BACKGROUND Amifostine was developed to protect normal tissues from radiation exposure. The current study was undertaken to determine whether amifostine would allow the delivery of greater numbers of weekly paclitaxel treatments with concomitant, hyperfractionated radiotherapy in pat
## Abstract ## Background. A phase II study was conducted using concurrent paclitaxel, carboplatin, and external beam radiotherapy (RT) in patients with advanced head and neck cancer. ## Methods. Forty‐three patients (stage III, __n__ = 12; stage IV, __n__ = 31) were treated with 8 cycles of wee