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Concordant loss of fragile gene expression early in breast cancer development

✍ Scribed by Gulnur Guler; Aysegul Uner; Nilufer Guler; Shuang-Yin Han; Dimitrios Iliopoulos; Peter McCue; Kay Huebner

Book ID
115175539
Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
279 KB
Volume
55
Category
Article
ISSN
1320-5463

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## Abstract A novel breast cancer cell line (RAO‐3) was established by transduction of the Q61L mutant RAS into human mammary epithelial cells that were immortalized with catalytic subunit of telomerase (__hTERT__). The cells displayed anchorage‐independent growth and proliferation, and formed huma