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Concordance of combination and single agent chemosensitivity prediction in ovarian carcinoma using the subrenal capsule xenograft assay (SRCA)

โœ Scribed by Joan A. Stratton; Mark A. Rettenmaier; Paul R. Kucera; Michael L. Berman; Philip J. DiSaia


Book ID
119052995
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
418 KB
Volume
30
Category
Article
ISSN
0090-8258

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Thirty-seven of 54 human squamous head and neck carcinomas were successfully grown as first transplant generation xenografts under the kidney capsule of conventional mice immunosuppressed by daily treatment with 60 mg/kg of cyclosporine. Of the 18 different tumors evaluated for chemosensitivity, 39%