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Concomitant Cisplatin and Hyperfractionated Radiotherapy in Locally Advanced Head and Neck Cancer: 10-Year Follow-Up of a Randomized Phase III Trial (SAKK 10/94)

✍ Scribed by Pirus Ghadjar; Mathew Simcock; Gabriela Studer; Abdelkarim S. Allal; Mahmut Ozsahin; Jacques Bernier; Michael Töpfer; Frank Zimmermann; Michael Betz; Christoph Glanzmann; Daniel M. Aebersold


Book ID
118455435
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
459 KB
Volume
82
Category
Article
ISSN
0360-3016

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## Background: Both twice daily fractionated radiotherapy and concurrent cisplatin with once-daily radiotherapy have been shown to improve local disease control in patients with head and neck cancer. the objective of this phase i trial was to determine the maximum tolerated dose of cisplatin which