Concomitant Chronic Lymphocytic Leukemia and Multiple Myeloma: Proof of Common Clonal Origin

Frequent clonal abnormalities of chromos

Frequent clonal abnormalities of chromosome band 13q 14 in b-cell chronic lymphocytic leukemia: Multiple clones, subclones, and nonclonal alterations in 82 midwestern patients

✍ Loann C. Peterson; Leanna L. Lindquist; Stephanie Church; Neil E. Kay 📂 Article 📅 1992 🏛 John Wiley and Sons 🌐 English ⚖ 796 KB

We performed cytogenetic analyses of peripheral blood lymphocytes from 82 Midwestern B-cell chronic lymphocytic leukemia (B-CLL) patients. The cells were cultured with mitogens for 3 4 days. At least I 5 metaphase cells were analyzed in 79 (96%) cases. Fifty (63%) of the 79 patients had clonal chrom