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Concise Three-Component Synthesis of Defucogilvocarcin M.

✍ Scribed by Isao Takemura; Koreaki Imura; Takashi Matsumoto; Keisuke Suzuki


Publisher
John Wiley and Sons
Year
2004
Weight
8 KB
Volume
35
Category
Article
ISSN
0931-7597

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Concise Synthesis of Pyrrolidine and Ind
✍ Guillaume Lapointe; Dr. Kurt Schenk; Prof. Philippe Renaud πŸ“‚ Article πŸ“… 2011 πŸ› John Wiley and Sons 🌐 English βš– 290 KB πŸ‘ 1 views

## Abstract The synthesis of pyrrolidine and indolizidine derivatives through radical carboazidation of alkenes with α‐iodoketones, followed by reductive amination, is described. When properly substituted, further lactamization afforded pyrrolizidinones in good yield. This carboazidation/reductive