Concise synthesis of pyridyl sulfides direct nucleophilic displacement of haloheteroaromatics by mercaptan promoted by K-Selectride

✍ Scribed by Eiji Takashiro; Yuji Nakamura; Katsumi Fujimoto

• Book ID: 104261821
• Publisher: Elsevier Science
• Year: 1999
• Tongue: French
• Weight: 205 KB
• Volume: 40
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(99)01038-2

✦ Synopsis

A simple and efficient synthetic method for sulfides from halogenated heteroaromatic compounds is described.

An alkylthioborate, generated from K-Selectride and a thiol, rapidly reacted with various haloheteroaromatics under mild conditions.