Concise Synthesis of Multiply Substituted Stereodefined cis,cis-2,4-Diene-1,6-dials, cis,cis-2,4-Diene-1,6-diols and Further Applications.
β Scribed by Guoliang Mao; Congyang Wang; Jinglong Chen; Ayako Muramatsu; Zhenfeng Xi
- Publisher
- John Wiley and Sons
- Year
- 2005
- Weight
- 31 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0931-7597
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Intramolecular cyclization of bis(3chloropropyl)-diethoxythiophosphorylacetonitrile 7, taking place under distillation in vacuo, yields 6-cyano-2-oxa-10-thia-1-phosphabicyclo[4.4.0]decane-1oxide 10 as a mixture of cis and trans isomers in a 2.3:1 ratio. The isomers were separated chromatographically