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Concise syntheses of l-α-phosphatidyl-d-myo-inositol 3-phosphate (3-PIP), 5-phosphate (5-PIP), and 3,5-bisphosphate (3,5-PIP2)

✍ Scribed by J.R Falck; U.Murali Krishna; Kishta Reddy Katipally; Jorge H Capdevila; Emin T Ulug


Book ID
104210262
Publisher
Elsevier Science
Year
2000
Tongue
French
Weight
154 KB
Volume
41
Category
Article
ISSN
0040-4039

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✦ Synopsis


phospholipids as well as short chain and crosslinkable aminoether analogs were achieved in ®ve to seven steps from a readily available myo-inositol derivative.


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Synthesis of l-α-phosphatidyl-d-myo-inos
✍ Asuka Nishikawa; Shintaro Saito; Yuichi Hashimoto; Kenji Koga; Ryuichi Shirai 📂 Article 📅 2001 🏛 Elsevier Science 🌐 French ⚖ 73 KB

Efficient synthesis of L-a-phosphatidyl-D-myo -inositol 3,5-bisphosphate was achieved from 1,2,5,6-diisopropylidene-Dglucose by utilizing ring-closing metathesis and catalytic OsO 4 dihydroxylation.