The asymmetric synthesis of β-lactam ant
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David A. Evans; J.Michael Williams
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Article
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1988
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Elsevier Science
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French
⚖ 332 KB
Imines derived from chiral a$-epoxyaldehydes have been shown to be useful chiral glyoxal imine synthons in the ketene-imine cycloaddition reaction. This process, which proceeds with high levels of reaction diastereoselection, affords enantiomerically pure &-substituted 3-amino-4alkylazetidinones in