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Concerning the reduction of alkyl halides by LiAlH4 evidence that AlH3 produced in situ is the one electron transfer agent.

✍ Scribed by E.C. Ashby; R.N. DePriest; T.N. Pham


Publisher
Elsevier Science
Year
1983
Tongue
French
Weight
253 KB
Volume
24
Category
Article
ISSN
0040-4039

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✦ Synopsis


The reduction of lo and 2' alkyl iodides by LiA1H4.has been shown to involve a radical intermediate formed by the reaction of the alkyl iodide with the AlH3 and LiI produced in situ in conjunction with LiAlH4 rather than by LiAlH4 alone, as evidenced by cyclized products in the reduction of 6-iodo-1-heptene, by the trapping of the radical and by stereochemical studies of the 2-halooctanes.