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Concerning the Mechanism of Action of Parathyroid Hormone I Ion-Gradients 1

โœ Scribed by Firschein, H.; Martin, G.; Mulryan, B. J.; Strates, B.; Neuman, W. F.

Book ID
125982014
Publisher
American Chemical Society
Year
1958
Tongue
English
Weight
644 KB
Volume
80
Category
Article
ISSN
0002-7863

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## Abstract In the growth plate chondrocyte, parathyroid hormone (PTH) stimulates phosphoinositol 4, 5 bisphosphate (PIP~2~) degradation, which results in the rapid production of inositol (1,4,5) triphosphate (IP~3~). IP~3~ induced the release of calcium from an intracellular store, which caused a