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Concerning the decreased D-3-hydroxybutyrate dehydrogenase activity in the liver and heart of hyperthyroid rats

✍ Scribed by Rosa Lippolis; Paola Morini; Anna Rosa Conserva; Elisabetta Casalino; Elemente Landriscina

Publisher
Springer
Year
1990
Tongue
English
Weight
440 KB
Volume
93
Category
Article
ISSN
0300-8177

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✦ Synopsis

Whereas in rat liver mitochondria the hyperthyroid state causes an increase both in fatty acid unsaturation and in the Ea of D-3-hydroxybutyrate dehydrogenase and a decrease in phase transition temperature, in hyperthyroid rat heart mitochondria these changes are negligible. D-3-hydroxybutyrate dehydrogenase in both the liver and the heart mitochondria of hyperthyroid rats is reduced by about 35% [12] but this reduction is not due to changes in membrane fluidity in either tissue. Hypothyroidism, on the other hand, affects BDH activity in neither heart nor liver.

πŸ“œ SIMILAR VOLUMES

The effect of fasting on D-3-hydroxybuty
The effect of fasting on D-3-hydroxybutyrate metabolism in the perfused rat heart
✍ A. M. N. Sultan πŸ“‚ Article πŸ“… 1990 πŸ› Springer 🌐 English βš– 731 KB

The effects of fasting for 24 h and 48 h on D-3-hydroxybutyrate utilization and acetoacetate, L-lactate and pyruvate production by the isolated non-working perfused rat heart were investigated over a wide range of DL-3-HB concentrations. D-3-HB utilization is concentration dependent and shows satura