✦ LIBER ✦

Concepts and comparisons in multidimensional separation

✍ Scribed by Giddings, J. C.

Publisher: John Wiley and Sons
Year: 1987
Tongue: English
Weight: 443 KB
Volume: 10
Category: Article
ISSN: 0935-6304
DOI: 10.1002/jhrc.1240100517

No coin nor oath required. For personal study only.

✦ Synopsis

Multidimensional separation methodology provides a mechanism for a very substantial increase in the resolving power of chromatographic and related systems. After defining the conditions required for multidimensional separation and reviewing the origin of its high resolving power, a comparison is drawn between the two principal kinds of multidimensional systems, represented by continuous two-dimensional operation and coupled column assemblies. It is shown that their roles are complementary. The two-dimensional system gives a broad powerful overview of a sample while the coupled column system can be used flexibly to magnify and resolve selected regions of the sample space.

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