Abstract
We detected nine perfluorinated compounds (PFCs) in 233 human wholeโblood samples collected from 12 cities (from 12 provinces and districts) in China. Perfluorinated compounds could be detected in all blood samples, with perfluorooctane sulfonate (C8, PFOS) as the most prominent PFC. Mean PFOS concentrations were measured at 3.06 to 34.0โยตg/L, accounting for the majority of the total perfluorinated compounds (ฮฃPFCs) (54โ87%) in blood samples, except those from Kunming. Perfluorooctane sulfonate and perfluorohexane sulfonate (C6, PFHxS) concentrations were positively correlated in blood samples (pโ<โ0.01). Significant relations among perfluorooctanoate (C8, PFOA), perfluorononanoic acid (C9, PFNA), perfluorodecanoic acid (C10, PFDA), and perfluoroundecanoic acid (C11, PFUnDA) (pโ<โ0.05) were also observed in the present study, indicating that they may come from a similar exposure pathway in China. In general, genderโrelated differences were found for PFHxS and ฮฃPFCs concentrations, which were significantly higher in males than in females (pโ<โ0.05). In the 20โ to 29โyear age group, gender influence was also found for PFHxS and PFOS concentrations. The mean blood concentration of PFOS (10.6โยตg/L) in the present study was comparable with results from other countries, while PFOA and PFHxS (1.39โยตg/L and 0.57โยตg/L, respectively) were often lower. This can probably be attributed to a different exposure pathway of the general population in China as compared to other countries. Environ. Toxicol. Chem. 2010;29:2695โ2701. ยฉ 2010 SETAC