𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Concentrations of N-methyl-2-pyrrolidone (NMP) and its metabolites in plasma and urine following oral administration of NMP to rats

✍ Scribed by Martin A. Carnerup; Anne Marie Saillenfait; Bo A.G. Jönsson

Book ID
116461455
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
139 KB
Volume
43
Category
Article
ISSN
0278-6915

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Determination of N-methyl-2-pyrrolidone
Determination of N-methyl-2-pyrrolidone and its metabolites in urine by micellar electrokinetic chromatography
✍ Lokajová, Jana ;Porras, Simo ;Elovaara, Eivor ;Wiedmer, Susanne 📂 Article 📅 2011 🏛 Walter de Gruyter GmbH 🌐 English ⚖ 473 KB

## Abstract A fast and accurate micellar electrokinetic capillary chromatography (MEKC) method was developed for monitoring N-methyl-2-pyrrolidone (NMP) exposure. Baseline separation of NMP and its main metabolites: 5-hydroxy-N-methyl-2-pyrrolidone (5HNMP), N-methylsuccinimide (MSI), 2-hydroxy-N-me

Comparative developmental toxicities of
Comparative developmental toxicities of the three major metabolites of N-methyl-2-pyrrolidone after oral administration in rats
✍ A. M. Saillenfait; J. P. Sabaté; F. Gallissot 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 187 KB

## Abstract The developmental toxicity of the three main metabolites of __N__‐methyl‐2‐pyrrolidone (NMP) was studied in Sprague‐Dawley rats. Pregnant rats were given 5‐hydroxy‐__N__‐methyl‐2‐pyrrolidone (5‐HNMP; 0, 250, 500, 750 or 1000 mg kg^−1^ day^−1^), __N__‐methylsuccinimide (MSI; 0, 500, 750,