Lamotrigine (LTG) is a new antiepileptic drug which is effective in refractory epilepsy and which has been shown to have weak antifolate properties in vitro. The effect of LTG on serum folate and red cell folate (RBC) concentrations was assessed in a series of 14 patients on short-term LTG treatment
Concentrations of lamotrigine in a mother on lamotrigine treatment and her newborn child
✍ Scribed by B. Rambeck; G. Kurlemann; S. R. G. Stodieck; T. W. May; U. Jürgens
- Publisher
- Springer
- Year
- 1997
- Tongue
- English
- Weight
- 110 KB
- Volume
- 51
- Category
- Article
- ISSN
- 0031-6970
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Efficacy and safety of lamotrigine (LTG) as add-on therapy was assessed in a randomised double-blind placebo-controlled trial of this drug in 23 adult patients with refractory partial seizures. Fifteen patients showed an improvement on LTG treatment, with a greater than 50% decrease in total seizure