Concanavalin A induced apoptosis in murine macrophage PU5-1.8 cells through clustering of mitochondria and release of cytochrome c

Detailing the role of Bax translocation,

Detailing the role of Bax translocation, cytochrome c release, and perinuclear clustering of the mitochondria in the killing of HeLa cells by TNF

✍ Bruna Pucci; Francesca Bertani; Natalie O. Karpinich; Manuela Indelicato; Matteo 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 248 KB

## Abstract Induction of cell death in HeLa cells with TNF and cycloheximide (CHX) required an adequate ATP supply and was accompanied by decrease in intracellular pH, translocation of Bax, perinuclear clustering of the mitochondria, and cytochrome __c__ release. The chloride channel inhibitor furo