Peptide synthesis by prior thiol capture
✍
D.S. Kemp; Nader Fotouhi
📂
Article
📅
1987
🏛
Elsevier Science
🌐
French
⚖ 233 KB
Disulfide interchange in DMSO, during amide formation by prior thiol capture is reduced to less than 3% at low concentrations (<lo M) of substrate in the absence of air and light, and in the presence of 2.5 to 10 mole % AgNo3T The rate and selectivity of the exchange process were assessed by reactin