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Computerized microimage analysis of age-related changes of the human sinoatrial node

โœ Scribed by Luo Bin; Song Yixuan; Zhu Jiazhen; Yao Qinsong; Liang Shangyou; Xie Jianhua

Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
403 KB
Volume
75
Category
Article
ISSN
0379-0738

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โœฆ Synopsis

This paper reports the age-related changes in the histological features of the sinoatrial node (SAN). The hearts of 106 persons dying at different ages (2 days-83 years), without clinical or pathological evidence of cardiac disease, were taken and divided into seven age-groups. Serial sections with a thickness of 2 microns, parallel to the long axis of the SAN, were prepared. Sections with the maximal area of the SAN were stained with hematoxylin/eosin (H & E) and Betty's method. The largest area of SAN were calculated by a computerized microimage analysis system. The age-related changes of the human SAN were discussed.

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